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229.522 0 Td [(a)-2.64358(c)-2.64358(r)-5.00129(o)-7.00239(s)2.71431(s)2.71431( )-208.716(a)-2.64358(l)0.356603(l)0.356603( )-208.716(d)-7.00239(o)-7.00239(m)17.4971(a)-2.64358(i)-11.7149(n)5.06907(s)2.71431( )-208.716(a)-2.64358(c)-2.64358(c)-2.64358(e)-2.64358(s)-9.35715(s)2.71431( )-208.716(t)0.356603(o)-7.00239( )-208.716(t)0.356603(h)5.06907(e)-2.64358( )-208.716(l)0.356603(a)-2.64358(r)-5.00129(g)5.06907(e)-2.64358( )-208.716(d)-7.00239(a)-2.64358(t)0.353656(a)-2.64653( )-208.716(s)2.71136(e)-2.64653(t)0.353656(s)2.71136(,)-3.5012( )-208.716(c)]TJ )8.5707( )-293.216(A)9.78449(n)5.06907( )-293.216(e)-2.64653(x)5.06907(a)-14.718(m)5.42862(p)]TJ [(g)5.06907(o)-7.00239( )-88.0014(t)0.356603(o)-7.00239( )-88.0014(s)2.71431(u)5.06907(p)-7.00239(p)-7.00239(o)-7.00239(r)-5.00129(t)0.356603( )-88.0014(i)0.356603(n)-7.00239(f)7.07018(o)-7.00239(r)-17.0728(m)17.4971(a)-2.64358(t)0.356603(i)0.356603(c)-14.715(s)2.7143(-)7.07018(r)-5.00129(e)-2.64358(l)0.356603(a)-14.715(t)0.356603(e)-2.64358(d)-7.00239( )-88.0014(r)-5.00129(e)-2.64358(s)2.71431(e)-2.64358(a)-2.64358(r)-5.00129(c)-2.64358(h)5.06907(. 218.341 0 Td 209.564 0 Td 214.854 0 Td -200.667 -13.2 Td [( )-75.93(i)0.356603(n)-7.00239(v)5.06907(e)-2.64358(s)-9.35715(t)-11.7149(m)5.42568(e)-2.64358(n)5.06907(t)-11.7149( )250]TJ )-3.50077( )-281.145(S)0.713207(i)-11.7178(n)-7.00239(c)-2.64653(e)9.42494( )250]TJ 206.077 0 Td 204.875 0 Td [(p)-7.00166(r)-5(o)5.06981(j)-11.7152(e)-2.64432(c)-2.64432(t)0.356603( )-39.7149(i)0.356603(s)2.71284( )-51.7863(m)17.4979(a)-2.64432(d)-7.00166(e)-2.64358( )-39.7149(p)-7.00166(o)-7.00166(s)2.71284(s)2.71284(i)0.356603(b)-7(l)0.356603(e)-2.64358( )-39.7156(b)-19.0724(y)17.142( )-39.7156(t)-11.7149(h)-7(e)-2.64211( )-39.7156(d)-7(a)-2.64358(t)0.356603(a)-2.64358( )-39.7156(s)2.71284(h)5.07055(a)-2.64358(r)-5.00129(i)0.356603(n)-7(g)5.07055( )-39.7166(c)-2.64358(a)-2.64358(p)-7(a)-2.64358(b)-7.00239(i)]TJ [(p)-7.00166(o)-7.00166(s)2.71321(i)0.356603(t)0.356603(o)-7.00166(r)-5.00129(y)17.1413( )-27.6437(f)7.07018(o)-7.00166(r)-5.00129( )-27.6434(m)17.4979(o)-7.00166(l)0.356603(e)-2.64432(c)-14.7158(u)5.07055(l)0.356603(a)-2.64358(r)-5.00129( )-15.5727(b)-7(i)0.356603(o)-7(l)0.356603(o)-7(g)5.07055(y)5.07055( )-15.5727(i)0.356603(n)-7(f)7.07018(o)-7(r)-17.0728(m)17.4971(a)-14.715(t)0.358077(i)0.356603(o)-7(n)5.07055(. [(i)0.356603(t)-11.7149(y)5.06907( )-75.93(o)-7.00239(f)7.07018( )-75.93(c)-2.64358(a)-14.715(r)-5.00129(e)-2.64358(. 0 g )-3.5012(9)-7.00239( )-75.93(t)]TJ [(t)-0.978454(s)1.5851( )-124.055(i)-2.54398(n)8.27446(f)-0.978454(o)-7.64825(r)-10.2118(m)18.0911(a)-7.64825(-)333]TJ medical research, effectiveness research and drug safety stu-dies [7]. [(F)0.713207(o)-7.00239(r)-5.00129( )-148.359(e)-2.64358(x)5.06907(a)-14.715(m)17.4971(p)-7.00239(l)0.356603(e)-2.64358(,)-3.5012( )-160.43(i)0.356603(n)-7.00239( )-160.43(A)9.78449(p)-7.00239(r)-5.00129(i)0.356603(l)0.356603( )-148.359(2)-7.00239(0)-7.00239(0)-7.00239(7)-7.00239(,)-3.5012( )-136.287(B)-9(B)-9(S)0.713207(R)3.07091(C)3.07091( )-148.359(e)-2.64358(s)-9.35715(t)0.356603(a)-2.64358(b)-7.00239(l)0.353656(i)0.353656(s)-9.3601(h)5.06907(e)-2.64653(d)-7.00239( )-148.359(a)-2.64653( )-148.359(n)5.06907(e)-26.7895(w)]TJ [(d)-7.00239(a)-2.64358(t)0.356603(a)-2.64358( )-63.8585(c)-2.64358(o)-7.00239(m)17.4971(p)-7.00239(l)0.356603(e)-2.64358(t)0.356603(e)-14.715(n)5.06993(e)-2.64358(s)2.71431(s)2.71431( )-63.8585(a)-14.715(n)5.06907(d)-7.00239( )-63.8585(d)-7.00239(a)-2.64358(t)0.356603(a)-2.64358( )-63.8585(q)5.06907(u)5.06907(a)-2.64358(l)0.356603(i)0.356603(t)-11.7149(y)5.06907(;)0.356603( )-63.8585(a)-2.64358(d)-7.00239(d)-7.00239(r)-5.00129(e)-2.64358(s)2.71431(s)2.71136(i)0.353656(n)-7.00239(g)5.06907( )-63.8585(r)-4.99834(e)-2.64653(g)-7.00239(u)]TJ 1 0 obj 207.28 0 Td 205.717 0 Td [(m)5.42862(m)5.42862(e)-14.718(n)-7.00239(d)-7.00239(e)-2.64653(d)5.06993( )]TJ 204.755 0 Td Q [( )-51.7871(r)-5.00129(e)-2.64358(d)-7.00239(u)5.06907(c)-14.715(i)0.356603(n)5.07202(g)-7.00239( )250]TJ [(R)-5.9364(e)10.3321(s)0.189848(e)10.3321(a)-4.62206(r)4.00871(c)-4.62206(h)6.51324( )-4.22046(C)-5.9364(o)21.4674(u)-8.44093(n)6.51324(c)-4.62206(i)-6.12624(l)8.82792( )250]TJ 4.16667 0 0 4.16667 0 0 cm BT [(r)-4.99834(c)-2.64653(h)5.06907( )-196.645(d)-7.00239(a)-14.718(t)0.353656(a)-2.64653(. -214.614 -13.32 Td [(l)-11.7152(y)17.1413( )-100.073(t)0.356235(h)5.06981(e)-2.64432( )-100.072(f)-5.00129(i)0.356603(r)-5.00129(s)2.71284(t)0.356603( )-100.072(s)2.71284(t)0.356603(e)-2.64432(p)-7(. [(e)-10.2118(n)8.27446(t)-0.981716( )-17.1817(m)18.0916(a)-7.64815(n)-5.0847(n)8.27446(e)-10.2118(r)3.14736(. [(n)5.06907(d)-7.00239(i)0.356603(n)-7.00239(g)5.06907( )-112.144(f)-5.00129(o)-7.00239(r)7.07018( )250]TJ -216.297 -13.2 Td [(s)2.71431(c)-2.64358(i)0.356603(e)-2.64358(n)5.06907(c)-2.64358(e)-2.64358( )-3.5012(a)-14.715(n)5.06907(d)-7.00239( )-3.5012(t)0.356603(e)-2.64358(c)-2.64358(h)-7.00239(n)5.06907(o)-7.00239(l)0.356603(o)-7.00239(g)-7.00239(y)17.1405( )-3.5012(r)-5.00129(e)-14.715(s)2.71431(e)-2.64358(a)-2.64358(r)-5.00129(c)-2.64358(h)5.06907( )-3.5012(o)-7.00239(u)5.06907(t)0.356603(s)-9.35715(i)0.356603(d)-7.00239(e)-2.64358( )-3.5012(o)-7.00239(f)7.07018( )-15.5727(m)17.5001(e)-2.64653(d)-7.00239(i)0.353656(c)-2.64653(i)-11.7178(n)5.06907(e)]TJ -227.959 -13.2 Td -210.887 -13.2 Td [(n)-7.00239(s)2.71431(t)0.356603(i)0.356603(t)-11.7149(u)5.06907(t)0.356603(e)-14.715( )250]TJ /R18 9.96 Tf [( )-51.7871(a)-2.64358(c)-2.64358(c)-2.64358(e)-14.715(s)2.71431(s)-9.35715( )-51.7871(t)0.35955(o)-7.00239( )250]TJ -208.121 -13.2 Td 229.282 0 Td [(a)-2.64653(t)0.353656(a)-2.64653( )250]TJ [(e)-2.64432(f)7.07055(f)7.07055(o)-7.00166(r)-5.00129(t)-11.7149(s)2.71284( )-208.715(t)0.356603(o)-7.00166( )-208.715(i)0.356603(n)5.06981(c)-2.64432(r)-5.00129(e)-2.64358(a)-2.64432(s)2.71284(e)-14.7158( )-208.716(a)-2.64358(d)-7(o)-7(p)-7(t)0.356603(i)0.356603(o)-7(n)5.07055( )-208.716(o)-7(f)7.07018( )-208.716(e)-2.64358(l)0.356603(e)-2.64358(c)-2.64358(t)0.356603(r)-5.00129(o)-7(n)5.07055(i)0.356603(c)-2.64358( )-220.788(h)5.07055(e)-2.64358(a)-2.64358(l)0.356603(t)-11.7149(h)5.06907( )-208.716(r)]TJ )-4.22046( )-4.22046(D)4.19856(e)]TJ [(m)5.42568(a)-2.64358(k)5.06907(e)-14.715( )-63.8585(t)-11.7149(h)5.06907(e)-2.64358( )-75.93(v)5.06907(a)-2.64358(s)2.71431(t)0.356603( )-63.8585(a)-14.715(m)5.42568(o)-19.0739(u)5.06907(n)5.06907(t)-11.7149( )-63.8585(o)-7.00239(f)7.07018( )-75.93(m)5.42568(e)-2.64358(d)-19.0739(i)0.356603(c)-2.64358(a)-2.64358(l)0.356603( )-63.8585(d)-7.00239(a)-2.64358(t)0.356603(a)-2.64358( )-63.8585(b)-7.00239(e)-2.64358(i)0.356603(n)-7.00239(g)5.06907( )-75.93(g)5.06907(e)-2.64653(n)5.06907(e)-2.64653(r)-4.99834(a)-2.64653(t)0.353656(e)]TJ [(s)2.71431(e)-2.64358(a)-2.64358(r)-5.00129(c)-2.64358(h)5.06907(. 205.837 0 Td [(g)-7.00239(y)5.06993( )-15.5727([)-4.99834(1)-7.00239(4)-7.00239(])-4.99834(. <> [(g)5.06907(r)-5.00129(o)-19.0739(w)21.856(. -215.936 -13.2 Td 232.408 0 Td 212.81 0 Td -213.411 -13.2 Td 222.068 0 Td -221.828 -13.2 Td [(m)5.42641(a)-2.64432(t)0.356235(i)0.356603(c)-14.7158(s)2.71284(,)-3.50046( )-3.50046(a)-2.64432(n)5.06981(d)-7.00166( )-3.50077(b)-7.00166(i)0.356603(o)-19.0731(m)17.4979(e)-2.64432(d)-7(i)0.356603(c)-2.64358(a)-2.64358(l)0.356603( )-3.5012(i)0.356603(n)-7(f)7.07018(o)-7(r)-17.0728(m)5.42568(a)-2.64358(t)0.356603(i)0.356603(c)-2.64358(s)2.71311(. [(d)-7.00239(r)-5.00129(u)5.06907(g)5.06907(. [(i)0.356603(l)0.356603( )-208.716(o)-7.00239(f)7.07018( )250]TJ 169.887 0 Td -218.822 -13.2 Td )-15.5722( )]TJ -219.423 -23.28 Td Retrieval of administrative/clinical data from medical records c. Interviewing research participants d. Phone survey of patients upon discharge e. Research design f. Data entry and simple data analyses g. Work with a cross-departmental research team h. Particular research protection and ethical concerns when research subjects have impaired 206.678 0 Td 0 G [(i)0.356603(n)5.06907(t)0.356603(e)-2.64358(r)-5.00129(a)-2.64358(c)-2.64358(t)0.356603( )-15.5727(w)9.78449(i)0.356603(t)-11.7149(h)5.06907( )-3.50077(e)-2.64358(a)-2.64358(c)-14.715(h)5.06907( )-3.5012(o)-7.00239(t)0.356603(h)5.06907(e)-2.64358(r)-5.00129( )-3.5012([)-5.00129(2)-7.00239(])-5.00129(. -219.062 -13.2 Td [(v)5.06907(a)-2.64653(i)0.353656(l)0.353656(a)-2.64653(b)-7.00239(l)0.353656(e)-2.64653( )-136.287(t)0.353656(o)5.06907( )250]TJ 199.945 0 Td stream [(i)-2.53165(n)-0.949354( )-0.474532(M)-2.68942(e)-1.84432(d)-0.949064(i)-2.53165(c)3.16518(a)-1.84432(l)-2.53165( )4.53496(R)0.737359(e)-1.84432(s)-1.74036(e)-1.84432(a)-1.84432(r)-2.63561(c)-1.84432(h)4.06014( )]TJ [(u)5.06981(s)2.71321(e)-2.64432( )-63.8582(t)-11.7149(h)5.06981(e)-14.7158(m)5.42641( )-63.8578(i)0.356603(n)5.06981( )-75.9296(t)0.356603(h)5.06981(e)-2.64432( )-63.8578(U)-14.3592(n)5.07055(i)0.356603(t)0.356603(e)-2.64358(d)-7( )-63.8585(K)-2.28845(i)-11.7149(n)-7(g)5.07055(d)-7(o)-7(m)17.4971(. [( )-160.43(t)0.353656(h)5.06907(e)-2.64653( )-172.502(U)-2.28698(n)5.06907(i)-11.7178(t)-11.7178(e)-2.64653(d)5.06907( )250]TJ 220.625 0 Td 204.514 0 Td (C)Tj 23 0 obj [(n)5.06907(d)-7.00239( )-281.145(o)-7.00239(t)0.356603(h)5.06907(e)-2.64063(r)-17.0728( )250]TJ [(b)-7.00239(l)0.356603(i)0.356603(c)-2.64358( )-88.0014(p)-19.0739(r)-5.00103(o)-7.00239(-)333]TJ 235.173 0 Td 214.013 0 Td [(a)-2.64358(v)5.06907(a)-2.64358(i)0.356603(l)0.356603(a)-2.64358(b)-7.00239(l)0.356603(e)-2.64358( )-3.5012(f)7.07018(o)-7.00239(r)-5.00129( )-15.5727(w)21.856(o)-7.00239(r)-17.0728(k)5.06907(i)-11.7149(n)5.06907(g)5.06907( )-15.5722(w)9.78449(i)-11.7149(t)0.356603(h)5.06907( )-3.5012(t)-11.7149(h)5.06907(e)-14.715( )-3.5012(d)-7.00239(a)-2.64358(t)0.356603(a)-2.64421( )-3.5012([)-5.00129(6)-7.00239(])7.07044(. [(t)0.356235(o)-7.00166(r)-5(s)2.71311(. -210.045 -13.2 Td [(t)0.353656(h)5.06907(a)-2.64653(t)0.353656( )-15.5727(s)2.71137(t)-11.7178(a)-2.64653(t)0.353656(e)-2.64653( )250]TJ [(t)0.356235(o)-7.00166(o)-7.00166(l)0.356235(s)2.71311(. 211.608 0 Td -207.039 -13.32 Td )-3.50077( )-75.9293(T)-16.7162(h)5.06981(e)-2.64432( )-88(N)-2.28771(I)-5.00129(H)-2.28845( )-88.0014(a)-2.64358(l)0.356603(s)2.71284(o)-7( )-88.0014(r)-5.00129(u)5.07055(n)5.07055(s)-9.35863( )-88.0014(t)0.356603(h)5.07055(e)-2.64358( )-88.0014(H)-2.28845(i)-11.7149(g)5.07055(h)5.07055( )-88.0014(P)-11.3568(e)-2.64358(r)-5.00129(f)7.07018(o)-7(r)-17.0728(m)17.4971(a)-14.718(n)5.06907(c)-2.64358(e)-2.64358( )-88.0014(C)]TJ )8.5707( )]TJ [(i)0.353656(t)-11.7178(h)5.06907( )-88.0014(t)-11.7178(h)5.06907(e)-2.64653( )-88.0014(p)-7.00239(r)-4.99834(i)0.353656(-)333.003]TJ -229.643 -13.2 Td [(o)-7.00239(r)-4.99834(e)-2.64653( )-51.7871(c)-2.64653(o)-7.00154(m)5.42862(-)333.003]TJ [(i)0.356235(n)5.06981( )-15.5723(p)-7.00166(a)-2.64432(r)-5.00129(t)0.356603(,)-3.50046( )-27.6434(w)21.8552(i)0.356603(t)-11.7149(h)5.06981( )-15.5719(p)-7.00166(u)5.06981(b)-7(l)0.356603(i)0.356603(c)-2.64432( )-15.5727(f)-5.00129(u)-7.00154(n)5.07055(d)-7(i)0.356603(n)-7(g)5.07055(. -224.473 -13.2 Td [(e)-2.64432(x)5.06981(a)-14.7158(m)17.4979(p)-7.00166(l)0.356603(e)-2.64432(,)-3.50046( )-39.7149(R)3.06944(e)-2.64432(p)-7.00166(. [(c)-2.64358(a)-2.64358(B)-9(I)-5.00129(G)-2.28791( )-63.8585(h)5.06907(a)-2.64358(s)2.71431( )-63.8585(a)-2.64358(l)0.356603(r)-5.00129(e)-2.64358(a)-2.64358(d)-7.00239(y)17.1405( )-75.9296(y)17.1405(i)0.356603(e)-2.64358(l)0.356603(d)-7.00239(e)-2.64358(d)-7.00239( )-63.8581(i)-11.7149(m)5.42568(p)-7.00239(o)-7.00239(r)-5.00129(t)0.356603(a)-2.64358(n)5.06907(t)0.356603( )-63.8585(a)-2.64358(p)-7.00239(p)-7.00239(l)0.353656(i)0.353656(c)-2.64653(a)-2.64653(t)0.353656(i)0.353656(o)-7.00239(n)5.06907(s)2.71136( )-63.8585(f)7.07312(o)]TJ /R8 5.04 Tf )-3.50077( )-39.7156(B)-21.072(y)5.06907( )-39.7156(t)0.353656(u)5.06907(r)-17.0698(n)5.06907(-)333.003]TJ [(h)5.06907(a)-2.64358(s)2.71431( )-172.502(e)-14.715(x)5.06907(p)-7.00154(e)-2.64358(r)-5.00129(i)0.356603(e)-2.64358(n)5.06907(c)-2.64358(e)-2.64358(d)-7.00239( )-172.502(s)2.71431(o)-19.0739(m)17.4971(e)-2.64358( )-184.573(n)5.06907(o)-7.00239(t)0.356603(a)-2.64358(b)-7.00239(l)-11.7149(e)-2.64358( )-172.502(s)2.71431(u)5.06907(c)-2.64358(c)-2.64358(e)-2.64358(s)-9.35715(s)2.71431(e)-2.64358(s)2.71431(,)-3.5012( )-184.573(f)7.07312(o)-7.00239(r)-4.99834( )-172.502(e)-2.64653(x)5.06907(a)-14.718(m)17.5001(p)-7.00239(l)0.353656(e)]TJ )-3.50077( )-196.645(F)0.713207(o)-7(r)-5.00129( )-196.645(e)-2.64358(x)-7(a)-14.715(m)17.4971(p)-7(l)0.356603(e)-2.64358(,)-3.5012( )-196.645(r)-5.00129(e)-2.64358(s)2.71284(e)-2.64358(a)-2.64358(r)-5.00129(c)-2.64358(h)5.07055(e)-2.64358(r)-5.00129(s)2.71284( )-208.716(h)5.06907(a)-2.64358(v)5.06907(e)-2.64358( )]TJ 0.998087 0 0 1 342 625.44 Tm -218.581 -13.32 Td )-3.50077( )-15.5727( )]TJ 209.564 0 Td [(p)-7.00166(a)-2.64432(c)-2.64432(k)5.06981(a)-2.64432(g)5.06981(e)-2.64432(. 178.664 0 Td -207.881 -13.2 Td [(t)0.356603(h)5.06907(e)-2.64358( )-15.5727(p)-7.00239(r)-5.00129(i)-11.7149(m)17.4971(a)-2.64358(r)-17.0728(y)17.1405( )-15.5727(i)-11.7149(n)5.06907(v)5.06907(e)-14.715(s)2.71431(t)-11.7149(m)5.42568(e)-2.64358(n)5.06907(t)0.356603( )-15.5727(b)-7.00239(e)-2.64358( )-15.5727(f)7.07018(o)-7.00239(r)-5.00129( )-15.5722(d)-7.00239(a)-2.64358(t)0.356603(a)-2.64358( )-15.5727(i)0.356603(n)5.06907(f)7.07018(r)-5.00129(a)-2.64358(s)2.71431(t)0.356603(r)-17.0728(u)5.06907(c)-2.64653(t)-11.7178(u)5.06907(r)-4.99834(e)-2.64653(. [(c)-2.64432(r)-5(e)-2.64432(a)-2.64432(t)0.356603(i)0.356603(n)5.06981(g)5.06981( )-341.501(t)-11.7149(h)5.06981(e)-2.64432( )-341.501(R)3.07018(o)-7.00166(a)-2.64432(d)-19.0731(m)17.4971(a)-2.64358(p)-7( )-353.574(w)21.8545(a)-14.715(s)2.71284( )-341.502(t)0.358077(o)-7( )-341.502(e)-2.64358(n)5.07055(s)2.71284(u)5.07055(r)-5.00129(e)-2.64358( )-341.502(t)0.356603(h)5.07055(a)-2.64358(t)0.356603( )-341.502(t)0.356603(h)5.07055(e)-14.715(s)2.71136(e)-2.64358( )-341.502(p)-7.00239(r)-5.00129(o)-7.00239(g)5.06907(r)]TJ [( )-160.43(r)-4.99834(e)-2.64653(s)2.71136(e)-2.64653(a)-14.718(r)-4.99834(c)-2.64653(h)5.06907( )250]TJ q [( )-196.645(n)-7.00239(e)-2.64421(t)0.356603(-)333]TJ endobj )-15.5722( )]TJ 26 0 obj 217.018 0 Td -220.265 -13.2 Td [(r)-5.00129(e)-2.64358(l)0.356603(e)-2.64358(v)5.06993(a)-2.64358(n)5.06907(t)0.356603( )-136.287(s)2.71431(t)0.356603(a)-14.715(k)5.06907(e)-14.715(h)5.06907(o)-7.00239(l)0.356603(d)-7.00239(e)-2.64358(r)-5.00129(s)2.7143( )-136.287([)-5.00129(1)-7.00154(8)-7.00239(])7.07018(. 230.244 0 Td [(e)-2.64432(x)5.06981(a)-14.7158(m)17.4979(p)-7.00166(l)0.356603(e)-2.64432(,)-3.50046( )-426.002(a)-14.7158(n)5.06981(a)-2.64432(l)-11.7149(y)17.142(z)-2.64432(i)-11.7149(n)-7.00166(g)5.06907( )-426.002(D)-2.28845(N)-14.3599(A)9.78302( )-426.002(s)-9.35863(e)-2.64211(q)-7(u)5.07055(e)-2.64358(n)5.07055(c)-2.64358(e)-2.64358(s)2.71284( )-426.002(o)-7.00301(r)-5.00129( )-438.074(m)17.4971(o)-7(d)-7(e)-2.64358(l)0.356603(i)0.356603(n)-7.00239(g)5.06907( )-426.002(p)-7.00239(r)-5.00129(o)-7.00239(t)0.356603(e)-2.64358(i)]TJ 201.629 0 Td [(s)2.71321(i)-11.7152(m)17.4979(p)-7.00166(l)-11.7149(y)5.06981( )-257.001(m)17.4979(a)-14.7158(k)5.06981(i)-11.7149(n)-7.00166(g)5.07055( )-244.931(a)-2.64432(l)0.356603(l)0.356603( )-244.93(p)-7(a)-2.64358(t)0.356603(i)0.356603(e)-2.64358(n)5.07055(t)0.356603( )-244.93(d)-7(a)-2.64358(t)0.356603(a)-2.64358( )-244.93(a)-2.64358(c)-2.64358(c)-2.64358(e)-2.64358(s)2.71284(s)2.71284(i)0.356603(b)-7(l)0.356603(e)-2.64421( )-244.93(f)7.07018(o)-7(r)-5.00129( )-244.93(r)-5.00129(e)-2.64358(s)2.71431(e)-2.64358(a)]TJ 210.646 0 Td [(n)5.06907( )-160.43(d)-7.00239(a)-2.64358(t)0.356603(a)-2.64358( )-172.502(f)7.07018(o)-7.00239(r)-5.00129( )250]TJ -234.692 -13.32 Td [(i)0.356603(s)-9.35715(m)17.4971( )-208.716(a)-14.715(n)5.06907(d)-7.00239( )-208.716(d)-7.00239(i)0.356603(s)2.71431(e)-2.64358(a)-2.64358(s)2.71431(e)-2.64358( )-208.716(o)-7.00239(u)5.06907(t)0.356603(b)-7.00239(r)-5.00129(e)-2.64358(a)-2.64358(k)-7.00239(s)2.7143(. )-3.50077( )-136.287(T)-16.7162(h)5.06907(e)-2.64358( )250]TJ [(d)-7.00239(e)-2.64358(v)5.06907(o)-7.00239(t)0.356603(e)-2.64358( )-27.6441(s)2.71431(i)0.356603(g)-7.00239(n)5.06907(i)-11.7149(f)7.07018(i)0.356603(c)-2.64358(a)-14.715(n)5.06907(t)0.356603( )-27.6441(r)-5.00129(e)-2.64358(s)2.71431(o)-7.00239(u)5.06907(r)-5.00129(c)-2.64358(e)-14.715(s)2.71431( )-27.6441(s)2.71431(i)-11.7149(m)17.4971(p)-19.0739(l)-11.7149(y)17.1405( )-27.6441(t)0.356603(o)-7.00239( )-39.7156(m)5.42568(a)-14.715(n)5.06907(a)-2.64653(g)5.06907(i)-11.7178(n)-7.00239(g)5.06907( )-27.6441(t)-11.7178(h)5.06907(e)]TJ [(r)-4.99834( )-112.144(d)-7.00239(a)-2.64653(t)0.353656(a)-2.64653( )-112.144(i)-11.7178(n)5.06907(-)333.003]TJ 63906 [(t)0.356603(e)-2.64358(c)-2.64358(h)5.06907(n)-7.00239(i)0.356603(c)-2.64358(a)-2.64358(l)0.356603( )-257.002(s)2.71431(t)0.356603(a)-14.715(n)5.06907(d)-7.00239(a)-2.64358(r)-5.00129(d)-7.00239(s)2.71431( )-257.002(a)-2.64358(n)5.06907(d)-7.00239( )-257.002(e)-2.64358(n)5.06907(a)-2.64358(c)-2.64358(t)0.356603(i)0.356603(n)-7.00239(g)5.06907( )-257.002(c)-2.64358(u)5.06907(l)0.356603(t)-11.7149(u)5.06907(r)-5.00129(a)-2.64358(l)0.356603( )-257.002(c)-2.64653(h)5.06907(a)-14.718(n)5.06907(g)5.06907(e)-2.64653( )-257.002(i)-11.7178(n)]TJ [(t)-6.12898(h)-8.44184(e)10.3294( )-4.22092(A)19.1546(m)0.383347(e)10.3294(r)4.00871(i)-6.12898(c)-4.6248(a)-4.6248(n)-8.44184( )10.7337(M)-8.25017(e)10.3294(d)6.51233(i)-6.12807(c)-4.6248(a)-4.6248(l)8.82519( )-4.22046(A)19.1527(s)0.191673(s)0.191673(o)6.51324(c)-4.62572(i)-6.12989(a)10.3285(t)-6.12989(i)-6.12989(o)6.51324(n)6.51324( )-4.22046(2)6.51324(8)6.51324(0)-8.4391( )-4.22046(\()4.00871(1)6.51324(9)6.51324(9)-8.44093(8)-8.44093(\))4.00871(:)8.82427( )10.7337(1)-8.44093(3)6.51324(1)6.51324(1)-8.44352(-)4.00871(1)]TJ )-4.22046( )10.7333( )]TJ 211.247 0 Td [(h)5.06907(e)-2.64358(a)-2.64358(l)0.356603(t)-11.7149(h)5.06907( )-3.5012(r)-5.00129(e)-2.64358(c)-2.64358(o)-7.00239(r)-5.00129(d)-7.00239(s)2.71431(. -214.253 -13.2 Td )-4.22046( )10.7337(C)-5.93731(a)-4.6248(s)15.1458(t)-6.12898(r)4.00871(o)6.51233(,)-4.22046( )-4.22046(�)10.3291(E)-2.12118(x)6.51233(p)-8.44184(l)8.82519(a)-4.6248(i)8.82519(n)-8.44184(i)8.82519(n)-8.44093(g)6.51324( )-4.22046(I)33.917(n)-8.44093(t)-6.12989(e)10.3285(r)4.00871(n)-8.44093(a)-4.62572(t)-6.12989(i)-6.12989(o)6.51324(n)6.51324(a)-4.62572(l)8.82427( )-4.22085(H)4.20038(e)10.3285(a)-4.62572(l)8.82427(t)-6.12989(h)-8.44093( )-4.22046(I)18.9629(T)12.833( )]TJ

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